Nanobody Binding to a Conserved Epitope Promotes Norovirus Particle Disassembly
نویسندگان
چکیده
منابع مشابه
Nanobody binding to a conserved epitope promotes norovirus particle disassembly.
UNLABELLED Human noroviruses are icosahedral single-stranded RNA viruses. The capsid protein is divided into shell (S) and protruding (P) domains, which are connected by a flexible hinge region. There are numerous genetically and antigenically distinct noroviruses, and the dominant strains evolve every other year. Vaccine and antiviral development is hampered by the difficulties in growing huma...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2014
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.03176-14